Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity
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منابع مشابه
Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity
Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size of cryptococcal cells is typically 5 to 10 microm. Cell enlargement was observed in vivo, producing cells up to 100 microm. These morphological changes in cell size affected pathogenicity via reducing phagocytosis by host mononuclear cells, increasing resistance to oxidative and nitrosative stress, and correlat...
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Fungal pathogens represent a leading cause of life-threatening infections in debilitated patients and exert a substantial toll on health care resources. A major development in the past few years, resulting from extremely rapid technological advances, has been the elucidation of the genome sequences of all of the major human fungal pathogens. Together with the development of transcriptomics and ...
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ژورنال
عنوان ژورنال: PLoS Pathogens
سال: 2010
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1000953